Detalhe da pesquisa
1.
Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis.
Nat Immunol
; 16(5): 485-94, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25822250
2.
Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.
Blood
; 129(18): 2479-2492, 2017 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28270450
3.
Disruption of Spermatogenesis and Infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2).
Cerebellum
; 18(3): 448-456, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30778901
4.
A new model to study neurodegeneration in ataxia oculomotor apraxia type 2.
Hum Mol Genet
; 24(20): 5759-74, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26231220
5.
Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2.
Hum Mol Genet
; 23(18): 4758-69, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24760770
6.
Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing.
PLoS Genet
; 9(4): e1003435, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23593030
7.
ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control.
J Biol Chem
; 286(36): 31542-56, 2011 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21757780
8.
Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage.
J Cell Biol
; 177(6): 969-79, 2007 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17562789
9.
CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response.
Nucleic Acids Res
; 38(5): 1489-503, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20008512
10.
Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage.
Hum Mol Genet
; 18(21): 4102-17, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19643912
11.
Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation.
Hum Mol Genet
; 18(18): 3384-96, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19515850
12.
Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype.
Cancer Res
; 66(6): 2907-12, 2006 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16540636
13.
Pivotal role of the beta-clamp in translesion DNA synthesis and mutagenesis in E. coli cells.
DNA Repair (Amst)
; 1(9): 703-8, 2002 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12509274
14.
Altered translesion synthesis in E. coli Pol V mutants selected for increased recombination inhibition.
DNA Repair (Amst)
; 2(12): 1361-9, 2003 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-14642565
15.
Senataxin controls meiotic silencing through ATR activation and chromatin remodeling.
Cell Discov
; 1: 15025, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-27462424
16.
R-loops in proliferating cells but not in the brain: implications for AOA2 and other autosomal recessive ataxias.
PLoS One
; 9(3): e90219, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24637776
17.
Senataxin protects the genome: Implications for neurodegeneration and other abnormalities.
Rare Dis
; 1: e25230, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-25003001
18.
Nucleolar localization of aprataxin is dependent on interaction with nucleolin and on active ribosomal DNA transcription.
Hum Mol Genet
; 15(14): 2239-49, 2006 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16777843
19.
Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase.
J Biol Chem
; 279(48): 50280-5, 2004 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-15385534
20.
Involvement of DnaE, the second replicative DNA polymerase from Bacillus subtilis, in DNA mutagenesis.
J Biol Chem
; 279(3): 1757-67, 2004 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-14593098